Factors predicting survival in patients with proximal gastric carcinoma involving the esophagus

Table 2 Univariate analysis of overall survival in patients with lymph node metastasis

		Overall survival
Characteristic	No. of patients (%)	HR	95% CI1		P value
Celiac axis lymph node
Negative	130 (92)	1.00
Positive	12 (8)	3.33	1.40	7.95	0.007
Perineural invasion
Negative	55 (38.7)	1.00
Positive	87 (61.3)	1.48	0.54	4.11	0.447
Number of nodes retrieved/case
10	21 (15)	1.00
≥ 11	121 (85)	1.48	0.72	3.06	0.290
≤ 15	46 (32)	1.00
≥ 16	96 (68)	2.29	1.24	4.22	0.008
≤ 23	100 (70)	1.00
≥ 24	42 (30)	1.15	0.65	2.03	0.627
Number of positive nodes/case
≤ 6	58 (41)	1.00
≥ 7	48 (34)	1.72	1.20	2.46	0.003
≤ 15	92 (65)	1.00
≥ 16	14 (10)	2.30	1.40	3.77	0.001
Lymph node ratio
0	36 (25)	1.00
≤ 0.2	40 (28)	1.34	0.61	2.97	0.467
> 0.2	66 (46)	2.28	1.15	4.51	0.018

¹Hazards ratios (HR), 95% confidence interval (CI) and P values for postoperative time to recurrence and overall survival were adjusted according to important clinical characteristics. Survival time was defined as the period from the surgical treatment to endpoint of follow-up.