Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers

doi:10.3748/wjg.v18.i27.3502

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 27

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4620)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-1) series, Tables (1-4) series.

Item

Count

PDF

472

HTML

3564

Figures (1-1)

293

Tables (1-4)

291

Sum=4620

Jul 21, 2012 (publication date) through Feb 27, 2025

Times Cited of This Article

Times Cited (8)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Gastroenterol. Jul 21, 2012; 18(27): 3502-3510
Published online Jul 21, 2012. doi: 10.3748/wjg.v18.i27.3502

Table 4 Articles reporting regenerating islet-derived type IV-targetted therapy

Author	Year	Method/type of cancer	Result
Bishunpuri et al[53]	2006	Transfection of rhR4/colorectal	Increase in pEGFR and pAkt
Takehara et al[20]	2006	Transfection of rhR4 and siRNA/pancreatic	Significant reduction in viable cells andincrease in pAkt
Legoffic et al[72]	2009	RegIV antibody injection/pancreatic	Significant reductions in Akt, Bcl-2 and Bcl-xL

rhR4: Recombinant human regenerating islet-derived type IV; RegIV: Human regenerating islet-derived type IV; siRNA: Small interfering RNA; pEGFR: Phosphorylated epidermal growth factor receptor; pAkt: Phosphorylated protein kinase B; Akt: Protein kinase B; Bcl-2: B-cell lymphoma 2; Bcl-xL: B-cell lymphoma-extra large.

Citation: Numata M, Oshima T. Significance of regenerating islet-derived type IV gene expression in gastroenterological cancers. World J Gastroenterol 2012; 18(27): 3502-3510
URL: https://www.wjgnet.com/1007-9327/full/v18/i27/3502.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i27.3502