Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma

Table 3 Prognostic significance of the clinical factors influencing survival

Multivariate	Hazard ratio	95% CI	P value
Age (≥ 60 yr, < 60 yr)	1.381	0.403-4.734	0.608
Sex (male, female)	1.462	0.433-4.937	0.541
Child-Pugh classification	3.710	1.490-9.238	0.005
Portal vein thrombosis (without, with)	0.086	0.019-0.387	0.001
Extent of HCC	0.185	0.051-0.679	0.011
(multinodular, massive > 50% of liver)
Bilirubin (≥ 3, < 3)	0.837	0.319-2.195	0.718
Albumin (< 3, ≥ 3)	1.059	0.430-2.603	0.901
PT INR (< 2.3, ≥ 2.3)	0.218	0.066-0.715	0.012

HCC: Hepatocellular carcinoma; PT INR: Prothrombin time international normalized ratio.