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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Jul 7, 2012; 18(25): 3183-3195
Published online Jul 7, 2012. doi: 10.3748/wjg.v18.i25.3183
Published online Jul 7, 2012. doi: 10.3748/wjg.v18.i25.3183
Table 2 Ghrelin antagonists under development for the treatment of obesity and type 2 diabetes
Ghrelin antagonists | |||
Drug | Company | Target | Status |
TZP-301 | Tranzyme Pharma | Obesity, metabolic syndrome | Lead optimization |
Two families of ghrelin antagonists | Helsinn Pharmaceuticals | Obesity, metabolic syndrome | Lead optimization |
AEZS-123 | Aeterna Zenartis | Obesity, alcohol abuse | Preclinical |
Ghrelin antagonist | Novartis (Elixir) | Type 2 diabetes, obesity | Preclinical |
- Citation: Verhulst PJ, Depoortere I. Ghrelin's second life: From appetite stimulator to glucose regulator. World J Gastroenterol 2012; 18(25): 3183-3195
- URL: https://www.wjgnet.com/1007-9327/full/v18/i25/3183.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i25.3183