Knockdown of liver-intestine cadherin decreases BGC823 cell invasiveness and metastasis in vivo

Figure 4 Protein profile differences between lenti-liver-intestine cadherin-miR-B and BGC823 cells. A, B: Comparison of protein profiles by 2-dimensional gel electrophoresis between BGC823 and lenti-liver-intestine cadherin (CDH17)-miR-B cells; C: Close-up image of differential expression of protein spots with intensity alterations > 3-fold and recurrence four or more times in independent experiments. The average intensity of each spot was determined using PDQuest 2-DE software; D: Cellular location of the 15 altered proteins identified by mass spectrometry; E: Molecular functions of the 15 altered proteins identified by mass spectrometry.