Function of chloride intracellular channel 1 in gastric cancer cells

Figure 5 Chloride intracellular channel 1 knockdown reduces apoptosis in gastric cancer cell lines. Apoptosis detection by flow cytometry. For each sample, 10 000 cells were counted, and the apoptotic cells were summarized in the right panel. A: Figure was obtained from SGC-7901 cells; B: Figure was obtained from MGC-803 cells; C: The apoptotic rate of the chloride intracellular channel 1 (CLIC1) specific small interference RNA (siRNA) 3 group obviously decreased in both SGC-7901 cells (62.24%, P = 0.000) and MGC-803 cells (52.67%, P = 0.000), compared with the control (CTRL) group; while there were no significant difference of cell apoptosis rate between the negative control group cells and the mock group cells. The experiment was done in triplicate. The figure represented one of the 3 experiments performed in duplicate. ^aP < 0.05, ^bP < 0.05 vs CTRL and mock.