Gastric mucosal damage in water immersion stress: Mechanism and prevention with GHRP-6

doi:10.3748/wjg.v18.i24.3145

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 28, 2012; 18(24): 3145-3155
Published online Jun 28, 2012. doi: 10.3748/wjg.v18.i24.3145

Table 2 The effect of growth hormone releasing peptide-6 on the plasma levels of stress-related factors in rats

	ET-1 (pg/mL)	Renin activity (pg/mL)	TXB2 (ng/mL)
WRS	152.23 ± 10.70^d	1.71 ± 0.59^d	311.31 ± 50.54^d
WRS + GHRP-6	115.11 ± 4.08^b	0.65 ± 0.29^a	125.84 ± 8.36^b
SR	97.11 ± 4.71	0.11 ± 0.03	69.93 ± 22.13

^aP < 0.05,

^bP < 0.01 vs WRS group;

^dP < 0.01 vs SR group. WRS: Water immersion restraint stress; SR: Simple restraint; GHRP-6: Growth hormone releasing peptide-6; ET-1: Endothelin-1; TXB2: Thromboxane B2.

Citation: Guo S, Gao Q, Jiao Q, Hao W, Gao X, Cao JM. Gastric mucosal damage in water immersion stress: Mechanism and prevention with GHRP-6. World J Gastroenterol 2012; 18(24): 3145-3155
URL: https://www.wjgnet.com/1007-9327/full/v18/i24/3145.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i24.3145