Alcohol consumption in patients with primary sclerosing cholangitis

Table 2 Comparison of clinical variables and alcohol consumption between patients with and without significant fibrosis

Variable	Non-significant fibrosis (n = 70)	Significant fibrosis (n = 26)	P value
Duration of disease (yr)	10.1 ± 6.8	15.6 ± 7.9	0.019
Age at primary sclerosing cholangitis diagnosis (yr)	36 ± 14	34 ± 13	0.29
Lifetime alcohol intake (unit)	3896 ± 4441	3845 ± 4457	0.44
Yearly alcohol intake, mean (unit)	144 ± 178	117 ± 135	0.27
Total occasions of binge-drinking	331 ± 692	194 ± 341	0.23
Yearly occasions of binge-drinking	12.7 ± 24.7	7.1 ± 13	0.41
Yearly alcohol intake, before diagnosis (unit)	111 ± 129	103 ± 141	0.24
Yearly alcohol intake, after diagnosis (unit)	151 ± 200	88 ± 86	0.26
Yearly binge drinking episodes, before diagnosis	14.9 ± 38.1	4.3 ± 7.3	0.07
Yearly binge drinking episodes, after diagnosis	9.6 ± 18.6	3.6 ± 4.7	0.23
Bilirubin (μmol/L)	11.8 ± 6.8	24.8 ± 23.1	0.015
Alkaline phosphatase (μkat/L)	2.66 ± 2.65	2.66 ± 2.22	0.45
Phosphatidyl ethanol (μmol/L)	0.33 ± 1	0.1 ± 0	0.0016
Carbohydrate deficient transferrin (%)	1.06 ± 0.38	0.88 ± 0.2	0.02
Body mass index (kg/m²)	24.12 ± 3.12	24.02 ± 4.24	0.43