Effects of anesthetic methods on preserving anti-tumor T-helper polarization following hepatectomy

Table 3 Comparison of T-helper 1, T-helper 2, T-helper 17, regulatory T cell frequencies and T-helper 1/T-helper 2 cell ratio between G + E and G anesthesia groups

Variables	G + E group (%)	G group (%)	P
Th1
d0	7.44 ± 1.54	7.38 ± 1.35	0.87
d2	14.66 ± 1.96	20.42 ± 2.77	0.098
d7	16.57 ± 0.96	10.37 ± 0.84	< 0.001
Th2
d0	1.08 ± 0.14	1.14 ± 0.12	0.745
d2	2.64 ± 0.30	3.98 ± 0.49	0.028
d7	0.73 ± 0.07	1.14 ± 0.17	0.231
Th17
d0	2.80 ± 0.26	2.65 ± 0.36	0.424
d2	2.56 ± 0.30	3.01 ± 0.38	0.374
d7	1.08 ± 0.10	1.45 ± 0.15	0.047
Treg
d0	5.44 ± 0.26	6.62 ± 0.45	0.372
d2	7.42 ± 0.60	6.43 ± 0.46	0.194
d7	4.51 ± 0.56	6.19 ± 0.80	0.003
Th1/Th2 ratio
d0	8.63 ± 1.76	7.62 ± 1.32	0.688
d2	9.67 ± 1.94	7.40 ± 1.26	0.253
d7	14.64 ± 0.56	6.03 ± 0.83	< 0.001

Student’s t test. G: General anesthesia; E: Epidural block; Th: T-helper; Treg: Regulatory T cell.