WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721

Figure 7 Overexpression of WWOX suppresses the phosphorylation of p-AKT(Thr308) and p-AKT(Ser473). A: p-AKT(Thr308) levels were decreased in pEGFP-WWOX cells compared with parental and control vector transformed cells by Western blotting analysis; B: p-AKT(Ser473) levels were decreased in pEGFP-WWOX cells compared with parental and control vector transformed cells by Western blotting analysis. Data are presented as mean ± SD (P < 0.05). 1: Control group; 2: Empty vector transfection group; 3: pEGFP-WWOX transfection group. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.