Hepatocellular carcinoma and macrophage interaction induced tumor immunosuppression via Treg requires TLR4 signaling

Figure 4 Tumor necrosis factor-α, interleukin-10, and CCL22 mRNA expression in RAW246. 7 and RAW246.7 cells co-cultured with H22 cells ± lipopolysaccharide. The bars indicate the relative amount of tumor necrosis factor (TNF)-α, interleukin (IL)-10 and CCL22 mRNA expression (reverse transcriptase polymerase chain reaction). LPS: Lipopolysaccharide. ^bP < 0.001 vs RAW co-culture.