Stem cell factor-mediated wild-type KIT receptor activation is critical for gastrointestinal stromal tumor cell growth

Figure 3 Western blotting analysis of phosphorylated KIT. A: KIT phosphorylation (p-KIT Y703) was analysed in gastrointestinal stromal tumor (GIST) samples (n = 51). A representative western blotting of p-KIT Y703 (top) and glyceraldehyde 3-phosphate dehydrogenase (GAPDH) (bottom) in patients with exon 11 or 9 mutations or wild-type c-kit-bearing tumors; B: GIST primary cells were incubated with 100 ng/mL stem cell factor (SCF) for the indicated times. KIT phosphorylation (p-KIT Y703) was analysed by western blotting.