Proteome profiling of spinal cord and dorsal root ganglia in rats with trinitrobenzene sulfonic acid-induced colitis

Figure 1 The establishment of colitis in trinitrobenzene sulfonic acid rats. Representative hematoxylin and eosin microscopic photos of the colon tissue (A) revealed inflammation in the sub-mucosa layer of trinitrobenzene sulfonic acid (TNBS) rats; measurement of myeloperoxidase (MPO) activity in wet colon tissue (B, 2.61 ± 2.47 vs 0.03 ± 0.01) and tumor necrosis factor-α (TNF-α) level in colonic total protein (C, 759.80 ± 81.07 vs 174.00 ± 31.92) revealed significantly elevated MPO activity and TNF-α level in TNBS treated group in comparison with saline control group. ^aP < 0.05 vs saline group.