WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721

doi:10.3748/wjg.v18.i23.3020

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Jun 21, 2012 (publication date) through Nov 1, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2012; 18(23): 3020-3026
Published online Jun 21, 2012. doi: 10.3748/wjg.v18.i23.3020

Table 1 Methyl thiazolyl tetrazolium assay

Cell line	Optical density value
SMMC-7721	1.77 ± 0.20
pEGFP-Nl/SMMC-7721	1.78 ± 0.13
pEGFP-Nl-WWOX/SMMC-7721	1.12 ± 0.23

The cell growth of parental SMMC-7721, control vector and WWOX over-expressing cells was examined by methyl thiazolyl tetrazolium assay over a 3-d period. The cell growth of the WWOX expressing cells (pEGFP-N1-WWOX/SMMC-7721) was reduced compared with the wild-type (SMMC-7721) and control vector (pEGFP-N1/SMMC-7721) cells (P < 0.05).

Citation: Hu BS, Tan JW, Zhu GH, Wang DF, Zhou X, Sun ZQ. WWOX induces apoptosis and inhibits proliferation of human hepatoma cell line SMMC-7721. World J Gastroenterol 2012; 18(23): 3020-3026
URL: https://www.wjgnet.com/1007-9327/full/v18/i23/3020.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i23.3020