Overexpression of metastasis-associated in colon cancer 1 predicts a poor outcome of hepatitis B virus-related hepatocellular carcinoma

Table 1 Basic clinical characteristics of patients with hepatitis B virus-related hepatocellular carcinoma (n = 354)

Clinical features	Stage A	Stage B	Stage C
Cases (n)	138	96	120
Median age (yr, range)	55 (24-68)	53 (29-70)	52 (21-72)
Male/female	118/20	82/14	106/14
Median tumor diameter (cm, range)	2.5 (1.5-3)	4.0 (3-5)	4.5 (2-6)
AFP (μg/L, > 400/ ≤ 400)	45/93	40/56	85/35
HBV DNA (+/-)	78/60	57/39	76/44
HBeAg (+/-)	50/88	32/64	54/66
ECOG PS (0/1/2)	92/30/16	60/25/11	25/55/40
Child-Pugh (A/B)	92/46	67/29	58/62
Tumor number (single/multinodular)	123/15	56/40	67/53
Invasion of portal vein (+/-)	0/138	0/96	120/0
Tumor differentiation (high/intermediate/low)	45/66/27	27/38/31	20/50/50

HBV: Hepatitis B virus; ECOG PS: Eastern Cooperative Oncology Group Performance Status Scale; AFP: α- fetoprotein; HBeAg: HBV e antigen.