Noninvasive assessment of hepatic fibrosis in Egyptian patients with chronic hepatitis C virus infection

Table 5 The accuracy of different ratios and indices in the diagnosis of early liver cirrhosis

Item	Cutoff value	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)	AUROC	P value
AAR	1.2	46	88.7	50	87.3	80.5	0.761	0.002
APRI	1.36	46.7	87.1	46.7	87.1	79.2	0.697	0.018
API	5.5	60	80.6	42.9	89.3	76.6	0.826	0.000
GUCI	1.56	60	85.5	50	89.8	80.5	0.783	0.001

AAR: Aspartate aminotransferase-to-alanine aminotransferase ratio; APRI: Aspartate aminotransferase-to-platelet ratio index; API: Age platelet index; GUCI: Göteborg University Cirrhosis Index; PPV: Positive predictive value; NPV: Negative predictive value; AUROC: Area under the receiver operating characteristics.