Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer

doi:10.3748/wjg.v18.i22.2745

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Jun 14, 2012 (publication date) through Dec 17, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 14, 2012; 18(22): 2745-2755
Published online Jun 14, 2012. doi: 10.3748/wjg.v18.i22.2745

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Figure 1 A model of DNA mismatch repair and molecular pathways for microsatellite instability+ colorectal cancers. A: A model of the proposed mechanism of mismatch repair (MMR) proteins, illustrating patterns of relevant heterodimerization; B: The models for colorectal cancer (CRC) carcinogenesis are presented in parallel for Lynch syndrome and sporadic cases. HNPCC: Hereditary nonpolyposis colorectal cancer; MSI: Microsatellite instability; CIMP: CpG island methylator phenotype; MSI: Microsatellite instability.

Citation: Yamamoto H, Adachi Y, Taniguchi H, Kunimoto H, Nosho K, Suzuki H, Shinomura Y. Interrelationship between microsatellite instability and microRNA in gastrointestinal cancer. World J Gastroenterol 2012; 18(22): 2745-2755
URL: https://www.wjgnet.com/1007-9327/full/v18/i22/2745.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i22.2745