GABA stimulates human hepatocellular carcinoma growth through overexpressed GABAA receptor theta subunit

Figure 3 The effect of gamma-aminobutyric acid on the growth of hepatocellular carcinoma cells. A: The effects of serial concentration gamma-aminobutyric acid (GABA) on proliferation of HepG-2 cells; B: Cell cycle measured by flow cytometry; C: Forty days after tumor cell injection, mice were sacrificed and tumor weight was recorded (n = 4, P < 0.01); D: Comparison of tumor weight (the left was tumor of mice injected with 0.9% NaCl only, the right was the tumor of mice treated with 40 μmoL/L GABA).