Key factors in developing the trinitrobenzene sulfonic acid-induced post-inflammatory irritable bowel syndrome model in rats

Figure 4 Effects of low dose trinitrobenzene sulfonic acid administration position and ethanol percentage on later acquired visceral hyperalgesia. Statistical analysis of pain threshold pressure at 4 wk and 8 wk after trinitrobenzene sulfonic acid (TNBS) administration are shown in panel (A) and (B), respectively. Data are shown as mean ± SE, n = 5 per group. ^bP < 0.01 vs saline-treated rats (one-way analysis of variance, Student-Newman-Keuls). AWR: Abdominal withdrawal reflex.