Serum inter-cellular adhesion molecule 1 is an early marker of diagnosis and prediction of severe acute pancreatitis

Table 4 Sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of acute physiology and chronic health evaluation II, intercellular adhesion molecule-1 and interleukin-6 in distinguishing severe acute pancreatitis from mild acute pancreatitis

	Cutoffs	Sensitivity(%)	Specificity(%)	PPV	NPV	PLR	NLR
APACHE-II	> 8	77.77	55.10	0.5600	0.7714	1.7320	0.2223
ICAM-1	25 ng/mL	61.11	71.42	0.6111	0.7142	2.1382	0.5445
IL-6	50 ng/mL	36.11	63.26	0.6190	0.5740	0.8826	1.1680

APACHE-II: Acute physiology and chronic health evaluation II; ICAM-1: Intercellular adhesion molecule-1; IL-6: Interleukin-6; PPV: Positive predictive value; NPV: Negative predictive value; PLR: Positive likelihood ratio; NLR: Negative likelihood ratio.