Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation

Table 2 Results of the preparation and endoscopic findings

Variable	Overall		Excluding patients with severe constipation		P value
	A (mosapride)	B (placebo)	C (mosapride)	D (placebo)	A vs B	C vs D
No. of patients	124	125	108	120
Time to first defecation (min, mean ± SD)	55.4 ± 27.3	71.2 ± 28.6	52.9 ± 26.2	70.4 ± 28.9	< 0.001	< 0.001
Frequency of defecation (times, median, quartile)	8.3 (4-18)	8.6 (4-18)	8.3 (4-18)	8.0 (4-18)	NS	NS
Time of bowel preparation (min, mean ± SD)	185.1 ± 63.8	198.0 ± 76.5	178.6 ± 58.2	198.0 ± 76.6	0.11	< 0.05
Elapsed time from last fluid intake to colonoscopy (min, mean ± SD)	154.6 ± 48.9	154.1 ± 48.2	157.1 ± 63.2	155.5 ± 62.1	NS	NS
Cecal intubation rate, n (%)	119 (96.0)	124 (99.2)	108 (100)	120 (100)	NS	NS
Insertion time1 (min, median, quartiles)	7.8 (2-55)	8.5 (2-38)	7.4 (2-55)	8.5 (2-38)	NS	NS
Feel of peristalsis, n (%)	20 (16.1)	22 (17.6)	14 (13.0)	22 (18.3)	NS	NS
Amount of irrigation fluid
None	67	65	57	62	NS	NS
< 50 mL	40	47	33	46
50-100 mL	15	11	12	11
> 100 mL	2	1	2	1
Endoscopic findings
Cancer	5	5	3	5
Polyps	70	82	61	79	NS	NS
Diverticulosis	32	39	29	38

P value by the Mann-Whitney U test.

¹Insertion time was based on patients in whom the cecal portion of the colon examined. NS: Not significant.