Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin

Figure 3 Modulation of gene expression by curcumin, (-)-epigallocatechin-3-gallate, lovastatin and their combinations. Esophageal cancer SKGT-4 and TE-8 cells were grown in monolayer overnight and treated with or without curcumin (Cur) (40 μmol/L), (-)-epigallocatechin-3-gallate (EGCG) (40 μmol/L), lovastatin (Lov) (4 μmol/L) and their combinations for 2 d and total cellular protein was extracted from the cells and subjected to Western blotting analysis of gene expression. Erk1/2: Extracellular-signal-regulated kinases; COX-2: Cyclooxygenase-2.