Suppression of esophageal cancer cell growth using curcumin, (-)-epigallocatechin-3-gallate and lovastatin

Figure 1 Suppression of esophageal cancer cell growth by curcumin, (-)-epigallocatechin-3-gallate, lovastatin and their combinations. Esophageal cancer SKGT-4 and TE-8 cells were grown in monolayer overnight and then treated with or without curcumin (Cur) (40 μmol/L), (-)-epigallocatechin-3-gallate (EGCG) (40 μmol/L), lovastatin (L) (4 μmol/L) and their combinations for up to 5 d. Methyl thiazolyl tetrazolium assays were then carried out to detect changes in cell viability (see Methods section). The experiments were repeated three times and the results are summarized as a % of the control (Con) (mean ± SD) and analyzed statistically using the Student’s t test. ^aP < 0.05, ^bP < 0.01.