Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells

Figure 8 Apoptosis induced by 5-aza-2’-deoxycitidine. SMMC-7721 and HepG2 cells were treated with 2 μmol/L DAC, 20 μmol/L cisplatin, or in combination for 72 h. A: The fluorescent microscopic pictures of apoptotic cells were captured by 4’,6-diamidino-2-phenylindole staining of the condensed and fragmented nuclei; B, C: Annexin V-fluorescein isothiocyanate (FITC) staining following facial action coding system analysis was shown for SMMC-7721 (B) or HepG2 cells (C). DAC: 5-aza-2’-deoxycitidine; Con: Control; CDDP: Cisplatin.