Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells

Figure 7 Sensitivity of SMMC-7721 and HepG2 cells to cisplatin enhanced by 5-aza-2’-deoxycitidine. A: Effects of DAC on growth inhibition. The hepatocellular carcinoma cell lines SMMC-7721 and HepG2 were treated with various doses of DAC for 72 h. Cell viability was determined by cell proliferation assay kit; B: The morphology of the cells was captured under a light microscope; C, D: SMMC-7721 (C) and HepG2 cells (D) cells were treated with 2 μmol/L DAC, 20 μmol/L cisplatin, or in combination for 72 h. Cell viability was determined by MTT assays. DAC: 5-aza-2’-deoxycitidine; Con: Control; CDDP: Cisplatin.