Preventive effects of geranylgeranylacetone on rat ethanol-induced gastritis

Figure 4 Ultrastructural changes under transmission electron microscope. A: Normal control group: the microvillis were arranged in neat rows and with no loss, organelles had integrated structure. intercellular junction were distinct (arrow, x 30 000); B: Model control group: widened cell gaps, vague intercellular junction(according to arrow), sparse and deciduous microvillis, and swelling mitochondria and endoplasmic reticulum (× 30 000); C: Low-dose geranylgeranylacetone treated group: the cells were arranged in neat rows and the intercellular junction were relative clear (arrow × 30 000), the structure of mitochondria and endoplasmic reticulum were mild swelling; D: High-dose geranylgeranylacetone treated group: the cells were arranged in neat rows and the intercellular junction were obvious clear (arrow × 30 000), the structure of mitochondria and endoplasmic reticulum were mild swelling.