Copyright
©2012 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2012; 18(17): 2084-2091
Published online May 7, 2012. doi: 10.3748/wjg.v18.i17.2084
Published online May 7, 2012. doi: 10.3748/wjg.v18.i17.2084
Figure 5 Low-grade brain edema.
Low-grade brain edema was determined by measuring the percentage brain water content in cirrhotic groups (closed bars) and control groups (open bars). Placebo-treated cirrhotic rats showed the presence of low-grade brain edema. Brain water content in rifaximin-treated cirrhotic rats was similar to that in control groups, and was significantly lower to that observed in placebo-treated cirrhotic rats. Insulin-like growth factor (IGF)-1 treatment did not diminish brain edema; brain water content in the cirrhosis + IGF-1 group was similar to that observed in the cirrhosis + placebo group. aP < 0.05 vs all control groups; cP < 0.05 vs cirrhosis + R. Cirr: Cirrhosis; Cont: Control; R: Rifaximin.
- Citation: Òdena G, Miquel M, Serafín A, Galan A, Morillas R, Planas R, Bartolí R. Rifaximin, but not growth factor 1, reduces brain edema in cirrhotic rats. World J Gastroenterol 2012; 18(17): 2084-2091
- URL: https://www.wjgnet.com/1007-9327/full/v18/i17/2084.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i17.2084