Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication

doi:10.3748/wjg.v18.i17.2043

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May 7, 2012 (publication date) through Jul 7, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2012; 18(17): 2043-2052
Published online May 7, 2012. doi: 10.3748/wjg.v18.i17.2043

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Figure 2 Bisulfite sequencing of secreted protein acidic and rich in cysteine in SMMC-7721 cell line. SPARC: Secreted protein acidic and rich in cysteine; TSS: Transcription start site; BS: Bisulfite sequencing; M: Methylation; U: Unmethylation; 5-Aza-CdR: 5-aza-2’-deoxycytidine; 1-18: CpG sites; - 119 to - 95, + 260 to + 282, + 52 to + 71, + 142 to + 163, + 36 to + 58, + 143 to + 167: Polymerase chain reaction primers position; Black dots: Methylation; Blank rings: Unmethylation.

Citation: Zhang Y, Yang B, Du Z, Bai T, Gao YT, Wang YJ, Lou C, Wang FM, Bai Y. Aberrant methylation of SPARC in human hepatocellular carcinoma and its clinical implication. World J Gastroenterol 2012; 18(17): 2043-2052
URL: https://www.wjgnet.com/1007-9327/full/v18/i17/2043.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i17.2043