Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis

Figure 5 Immunohistochemical staining of α-smooth muscle actin. A: Section of liver from controls showing negative staining (PAP × 125); B: Section of liver from liver fibrosis patients before treatment showing dense fibrotic reaction with strong positivity for α-smooth muscle actin (α-SMA) ↑↑ and dense mononuclear cellular infiltration ↑ (PAP × 225); C: Section of liver from conventional group after treatment showing dense mononuclear inflammatory infiltration ↑ and moderate positivity for α-SMA in fibrotic lesion↑↑ (PAP × 125); D: Section of liver from AHM group after treatment showing moderate mononuclear cellular infiltration ↑ surrounded by minimal fibrotic reaction stained mildly with α-SMA ↑↑ (PAP × 125).