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©2012 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2012; 18(17): 2043-2052
Published online May 7, 2012. doi: 10.3748/wjg.v18.i17.2043
Published online May 7, 2012. doi: 10.3748/wjg.v18.i17.2043
Table 7 Cox regression model of overall survival
| Factors | Univariate analysis | Multivariate analysis | ||||
| RR | 95% CI | P value | RR | 95% CI | P value | |
| Methylation | ||||||
| Positive | 2.672 | 0.999-7.147 | 0.044 | 3.207 | 1.290-7.975 | 0.012 |
| Negative | 1 | 1 | ||||
| Tumor size (cm) | ||||||
| > 5 | 5.293 | 1.560-17.959 | 0.008 | 8.045 | 2.125-30.456 | 0.002 |
| ≤ 5 | 1 | 1 | ||||
| AFP (μg/L) | ||||||
| > 400 | 3.306 | 1.421-7.694 | 0.006 | 7.105 | 1.798-28.080 | 0.005 |
| ≤ 400 | 1 | 1 | ||||
| Age (yr) | ||||||
| > 53 | 0.663 | 0.279-1.576 | 0.353 | |||
| ≤ 53 | 1 | |||||
| Gender | ||||||
| Male | 1.104 | 0.373-3.266 | 0.859 | |||
| Female | 1 | |||||
| Tumor number | ||||||
| Multiple | 3.330 | 1.440-7.704 | 0.005 | |||
| Single | 1 | |||||
| Vascular invasion | ||||||
| Positive | 2.776 | 1.186-6.502 | 0.019 | |||
| Negative | 1 | |||||
| Edmondson classification | ||||||
| I/II | 0.379 | 0.147-0.982 | 0.046 | |||
| III/IV | 1 | |||||
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Citation: Zhang Y, Yang B, Du Z, Bai T, Gao YT, Wang YJ, Lou C, Wang FM, Bai Y. Aberrant methylation of
SPARC in human hepatocellular carcinoma and its clinical implication. World J Gastroenterol 2012; 18(17): 2043-2052 - URL: https://www.wjgnet.com/1007-9327/full/v18/i17/2043.htm
- DOI: https://dx.doi.org/10.3748/wjg.v18.i17.2043