Macrophage secretory products induce an inflammatory phenotype in hepatocytes

doi:10.3748/wjg.v18.i15.1732

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Apr 21, 2012 (publication date) through Dec 27, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2012; 18(15): 1732-1744
Published online Apr 21, 2012. doi: 10.3748/wjg.v18.i15.1732

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Figure 6 In patients with chronic hepatitis C, increased hepatic mRNA expression of the macrophage marker CD163 (A) as well as matrix metalloproteinase-9 (B) was significantly associated with increasing stage of fibrosis (P < 0. 05 vs F0). C-E: Immunofluorescence in liver biopsies from patients with chronic hepatitis C demonstrated matrix metalloproteinase (MMP)-9 expression in CD163⁺ macrophages.

Citation: Melino M, Gadd VL, Walker GV, Skoien R, Barrie HD, Jothimani D, Horsfall L, Jones A, Sweet MJ, Thomas GP, Clouston AD, Jonsson JR, Powell EE. Macrophage secretory products induce an inflammatory phenotype in hepatocytes. World J Gastroenterol 2012; 18(15): 1732-1744
URL: https://www.wjgnet.com/1007-9327/full/v18/i15/1732.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i15.1732