Wnt5a participates in hepatic stellate cell activation observed by gene expression profile and functional assays

Table 2 Top 20 enriched Gene Ontology terms based on Gene Ontology classifications

Biological process	Count	Percent	Molecular function	Count	Percent	Cellular component	Count	Percent
Response to wounding	78	7.24	Cytoskeletal protein binding	73	6.78	Extracellular region part	125	11.61
Wound healing	46	4.27	Actin binding	52	4.83	Extracellular region	180	16.71
Regulation of cell growth	43	3.99	Growth factor binding	24	2.23	Extracellular matrix	69	6.41
Vasculature development	50	4.64	Glycosaminoglycan binding	24	2.23	Proteinaceous extracellular matrix	61	5.66
Actin cytoskeleton organization	42	3.90	Calcium ion binding	76	7.06	Extracellular matrix part	34	3.16
Actin filament-based process	43	3.99	Extracellular matrix structural constituent	14	1.30	Cytoskeleton	125	11.61
Blood vessel development	48	4.46	Heparin binding	19	1.76	Basement membrane	25	2.32
Cell migration	51	4.73	Polysaccharide binding	24	2.23	Extracellular space	71	6.59
Cell adhesion	72	6.69	Pattern binding	24	2.23	Cell projection	92	8.54
Biological adhesion	72	6.69	Insulin-like growth factor binding	11	1.02	Cytoskeletal part	88	8.17
Regulation of growth	55	5.11	Integrin binding	12	1.11	Cell surface	53	4.92
Regulation of cellular component size	46	4.27	Carbohydrate binding	39	3.62	Actin cytoskeleton	39	3.62
Extracellular matrix organization	27	2.51	Chemokine activity	10	0.93	Actin filament bundle	14	1.30
Regulation of cell proliferation	87	8.08	Chemokine receptor binding	10	0.93	Plasma membrane	216	20.06
Cytoskeleton organization	54	5.01	Protein complex binding	29	2.69	Collagen	12	1.11
Response to organic substance	109	10.1	Identical protein binding	57	5.29	Actomyosin	14	1.30
Response to hormone stimulus	72	6.69	Collagen binding	8	0.74	Stress fiber	13	1.21
Response to endogenous stimulus	77	7.15	Growth factor activity	20	1.86	Microtubule cytoskeleton	53	4.92
Cell motion	62	5.76	Platelet-derived growth factor binding	5	0.46	Cell leading edge	26	2.41
Blood vessel morphogenesis	38	3.52	Phospholipid binding	20	1.86	Vesicle lumen	15	1.39