Macrophage secretory products induce an inflammatory phenotype in hepatocytes

Table 1 Demographic and clinical features of patients with chronic hepatitis C virus infection

No. of patients	n	147
Age (yr)	mean ± SEM	42.3 ± 0.9
Sex	M/F	98/49
Viral genotype	1/ 2/ 3	80/6/61
Stage of fibrosis	0/1/2/3-4	13/65/44/25
Grade of steatosis	0/1/2-3	73/44/29
Necroinflammatory score	1-3/4-5/6-8	56/61/30
BMI (kg/m2)	mean ± SEM	26.2 ± 0.4
BMI	Lean, overweight, obese1	66/51/24
Alcohol - current (g/d)	Median (range)	1 (0-120)
Alcohol - past (g/d)	Median (range)	30 (0-500)
Creatinine (μmol/L)	mean ± SEM	77.8 ± 1.5
Platelets (× 109/L)	mean ± SEM	213 ± 6
Red blood cells (× 1012/L)	mean ± SEM	4.8 ± 0.3
Total WBC (× 109/L)	mean ± SEM	7.2 ± 0.2
Neutrophils (× 109/L)	mean ± SEM	4.0 ± 0.1
Lymphocytes (× 109/L)	mean ± SEM	2.3 ± 0.06
Monocytes (× 109/L)	mean ± SEM	0.6 ± 0.02

¹Lean: ≤ 25 kg/m²; overweight: > 25 and < 30 kg/m²; obese: ≥ 30 kg/m². BMI: Body mass index; WBC: White blood cell.