Heme oxygenase-1 prevents liver fibrosis in rats by regulating the expression of PPARγ and NF-κB

Figure 3 Effects of heme oxygenase-1 on hyaluronate acid, type IV collagen, hydroxyproline and α-smooth muscle actin expression. A: Levels of serum hyaluronate acid (HA); B: Levels of serum type IV collagen (IV-C); C: Quantity of liver hydroxyproline; D: Levels of liver alpha-smooth muscle actin (α-SMA) mRNA. Values are expressed as mean ± SE. ^aP < 0.01 vs the levels in group A; ^cP < 0.01 vs the levels in group C; ^eP < 0.05 vs the levels in group B; ^fP > 0.05 vs the levels in group B.