Heme oxygenase-1 prevents liver fibrosis in rats by regulating the expression of PPARγ and NF-κB

Figure 2 Effects of heme oxygenase-1 on the histopathology of rat liver fibrosis induced by CCl₄. A, F: Group A (normal, untreated); B, G: Group B (model for 4 wk, untreated); C, H: Group C (model for 6 wk, untreated); D, I: Group D (model for 6 wk, treated with zinc protoporphyrin IX from week 4 to week 6); E, J: Group E (model for 6 wk, treated with hemin from week 4 to week 6). A-E: Hematoxylin and eosin staining (magnification × 200); F-J: Masson staining of collagens (magnification × 200).