Prognostic significance of PTEN, Ki-67 and CD44s expression patterns in gastrointestinal stromal tumors

Figure 2 Kaplan-Meier cumulative survival plots of patients with gastric gastrointestinal stromal tumor. The end point was death due to gastrointestinal stromal tumor (GIST). A: High NIH risk assessment correlated significantly with worse outcomes in patients with gastric GIST (P = 0.004); B: PTEN labeling indexes (LIs) ≥ 50% correlated significantly with favorable outcomes in patients with gastric GIST (P = 0.006); C: In patients with gastric GIST, those with Ki-67 LIs < 5% had significantly more favorable outcomes than those with Ki-67 LIs ≥ 5% (P = 0.004); D: CD44s positivity was a significant, favorable indicator for patients with gastric GIST (P = 0.006); E: For patients with small intestinal GIST, the immunophenotype of PTEN LIs ≥ 50% and Ki-67 LIs < 5% was a favorable indicator (P = 0.009); F: Gastric GIST patients with immunophenotype of PTEN LIs ≥ 50%, Ki-67 LIs < 5% and CD44s positivity had significantly more favorable outcomes than those with other immunophenotypes (P = 0.011).