Dual regulatory role for phosphatase and tensin homolog in specification of intestinal endocrine cell subtypes

Figure 4 Loss of epithelial Pten signalling modulates circulating levels of glucose-dependent insulinotropic peptide and somatostatin. A: Analysis of circulating ghrelin level revealed no significant modulation between adult Pten^∆IEC mice (n = 10) and control littermates (n = 10); B: Analysis of circulating glucose-dependent insulinotropic peptide (GIP) level revealed a 1.5-fold increase in adult Pten^∆IEC mice (n = 10) when compared to control littermates (n = 10); C: Analysis of circulating somatostatin (SST) level revealed a 1.3-fold increase in adult Pten^∆IEC mice (n = 10) when compared to control littermates (n = 10). Error bars represent SE. ^aP < 0.05.