HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module

Figure 8 Inhibition of HBx-induced cell apoptosis by K252a. HepG2 cells were cultured in 0.01% dimethyl sulfoxide in the absence or presence of 300 nmol/L K252a after transfection with pcDNA3.1-X and incubated for 24 h, and the cell apoptosis was examined by flow cytometry. A: HepG2 group; B: pcDNA3.1-X transfected group; C: pcDNA3.1-X transfected + K252a group. Data are expressed as mean ± SD (n = 3), ^aP < 0.05 vs the HepG2 group; ^cP < 0.05 vs pcDNA3.1-X transfected group.