Notch3 regulates the activation of hepatic stellate cells

Figure 4 Over-expression of Notch3 intracellular domain increased the expression of myofibroblastic marker in hepatic stellate cell-T6. A: The expression of Notch3, α-smooth muscle actin (SMA) and collagen I were detected by Western blotting. Graphic representation of relative level of Notch3, α-SMA and collagen I normalized to β-actin; B: The expression of α-SMA and collagen I was also detected by immunofluorescence staining (x 400), ^aP < 0.05 vs control group.