Assessment of disease progression in patients with transfusion-associated chronic hepatitis C using transient elastography

doi:10.3748/wjg.v18.i12.1385

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 28, 2012; 18(12): 1385-1390
Published online Mar 28, 2012. doi: 10.3748/wjg.v18.i12.1385

Table 1 Characteristics of patients according to presence of hepatocellular carcinoma n (%)

Characteristics	HCC	Non-HCC	P value
Overall patients	n = 225	n = 291
Gender (M/F)	126/99	118/173	0.0005
Age (yr)¹	71.2 (66.1-75.7)	68.1 (58.7-72.4)	< 0.0001
Platelet count (10⁹/L)¹	95 (74-133)	161 (111-200)	< 0.0001
ALT (IU/L)¹	48 (34-68)	42 (25-69)	0.006
Alcohol consumption > 50 g/d	51 (22.7)	28 (9.6)	< 0.0001
Liver stiffness (kPa)¹	25.8 (17.3-37.4)	7.6 (5.6-13.9)	< 0.0001
IQR (kPa)¹	4.0 (2.5-6.0)	1.6 (1.2-2.6)	< 0.0001
Duration (17-29 yr)	n = 34	n = 64
Gender (M/F)	25/9	38/26	0.0028
Age (yr)¹	73.1 (65.7-77.1)	59.7 (47.2-69.2)	0.033
Platelet count (10⁹/L)¹	95 (76-154)	180 (116-229)	< 0.0001
ALT (IU/L)¹	51 (34-89)	42 (22-77)	0.2071
Alcohol consumption > 50 g/d	12 (35.3)	9 (14.1)	0.023
Liver stiffness (kPa)¹	26.1 (16.8-53.3)	5.9 (4.9-12.1)	< 0.0001
Duration (30-39 yr)	n = 40	n = 59
Gender (M/F)	16/24	23/36	0.9191
Age (yr)¹	72.0 (65.4-76.7)	62.3 (55.7-68.6)	< 0.0001
Platelet count (10⁹/L)¹	93 (68-120)	151 (97-215)	< 0.0001
ALT (IU/L)¹	42 (33-65)	48 (27-80)	0.7591
Alcohol consumption > 50 g/d	6 (15)	7 (11.9)	0.7641
Liver stiffness (kPa)¹	28.7 (20.1-37.8)	7.4 (5.7-13.8)	< 0.0001
Duration (40-49 yr)	n = 101	n = 127
Gender (M/F)	58/43	51/76	0.0113
Age (yr)¹	69.2 (65.8-73.6)	69.9 (65.7-72.7)	0.8107
Platelet count (10⁹/L)¹	97 (67-136)	163 (112-195)	< 0.0001
ALT (IU/L)¹	48 (34-69)	38 (23-64)	0.0080
Alcohol consumption > 50 g/d	25 (24.8)	8 (6.3)	0.0001
Liver stiffness (kPa)¹	25.1 (17.5-37.4)	8.2 (5.8-14.1)	< 0.0001
Duration (50-70 yr)	n = 50	n = 41
Gender (M/F)	27/23	18/23	0.4016
Age (yr)¹	74.4 (70.0-78.1)	73.7 (66.3-79.2)	0.5658
Platelet count (10⁹/L)¹	97 (81-141)	147 (117-189)	0.0001
ALT (IU/L)¹	52 (36-69)	46 (32-63)	0.1700
Alcohol consumption > 50 g/d	8 (16)	4 (9.8)	0.5363
Liver stiffness (kPa)¹	16.0 (8.0-36.3)	7.9 (6.5-15.8)	< 0.0001

¹Data are expressed as median (25th-75th percentiles). ALT: Alanine aminotransferase; IQR: Inter-quartile range; HCC: Hepatocellular carcinoma; M: Male; F: Female.

Citation: Masuzaki R, Tateishi R, Yoshida H, Arano T, Uchino K, Enooku K, Goto E, Nakagawa H, Asaoka Y, Kondo Y, Goto T, Ikeda H, Shiina S, Omata M, Koike K. Assessment of disease progression in patients with transfusion-associated chronic hepatitis C using transient elastography. World J Gastroenterol 2012; 18(12): 1385-1390
URL: https://www.wjgnet.com/1007-9327/full/v18/i12/1385.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i12.1385