Germline promoter hypermethylation of tumor suppressor genes in gastric cancer

doi:10.3748/wjg.v18.i1.70

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Jan 7, 2012 (publication date) through Dec 29, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jan 7, 2012; 18(1): 70-78
Published online Jan 7, 2012. doi: 10.3748/wjg.v18.i1.70

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Figure 7 Bisulfite sequencing of P16 promoter sequences. A: DNA isolated from the blood of a GC patient showing a T at all CpG sites of the P16 gene promoter region due to complete modification of the DNA; B: CpGenome Universal Methylated DNA control in which a high C content can be found at all CpGs in the P16 gene; C: CpGenome Universal Unmethylated DNA control showing a T at all CpG sites in the P16 gene promoter.

Citation: Wu PY, Zhang Z, Wang JM, Guo WW, Xiao N, He Q, Wang YP, Fan YM. Germline promoter hypermethylation of tumor suppressor genes in gastric cancer. World J Gastroenterol 2012; 18(1): 70-78
URL: https://www.wjgnet.com/1007-9327/full/v18/i1/70.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i1.70