Hepatoma cell line HepG2.2.15 demonstrates distinct biological features compared with parental HepG2

Figure 1 Ultrastructure of HepG2. 2.15 and HepG2 cells. A: Filopodia disappearance in HepG2.2.15 cells (EM × 2500); B: Viral inclusion bodies in the cytoplasm of HepG2.2.15 cells. Arrows indicate the viral inclusion bodies (EM × 15 000); C: Arrows indicate degenerated mitochondria (EM × 25 000); D: Plentiful filopodia around HepG2 cells. Arrows indicate filopodia (EM × 2500); E: Microfilament appearance in filopodia in HepG2 cells in high power field. Arrows indicate microfilament (EM × 25 000); F: Abundant organelles in the cytoplasm of HepG2 cells (EM × 25 000).