Diagnostic value of antigenemia assay for cytomegalovirus gastrointestinal disease in immunocompromised patients

doi:10.3748/wjg.v17.i9.1185

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Mar 7, 2011 (publication date) through Jan 8, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Mar 7, 2011; 17(9): 1185-1191
Published online Mar 7, 2011. doi: 10.3748/wjg.v17.i9.1185

Table 3 Comparison of diagnostic accuracy for detecting cytomegalovirus gastrointestinal disease between antigenemia assay and quantitative real-time polymerase chain reaction (n = 47)

	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)
CMV real-time PCR	73.00% (57.4-84.4)	100% (92.5-100)	100% (92.5-100)	50.00% (36.1-65.9)
CMV antigenemia assay	64.90% (50.7-79.1)	100% (92.5-100)	100% (92.5-100)	43.50% (28.3-57.8)

CMV: Cytomegalovirus; PPV: Positive predictive value; NPV: Negative predictive value; PCR: Polymerase chain reaction.

Citation: Nagata N, Kobayakawa M, Shimbo T, Hoshimoto K, Yada T, Gotoda T, Akiyama J, Oka S, Uemura N. Diagnostic value of antigenemia assay for cytomegalovirus gastrointestinal disease in immunocompromised patients. World J Gastroenterol 2011; 17(9): 1185-1191
URL: https://www.wjgnet.com/1007-9327/full/v17/i9/1185.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i9.1185