Yi-Qi-Zeng-Min-Tang, a Chinese medicine, ameliorates insulin resistance in type 2 diabetic rats

Table 4 General characteristics of diabetic rats after 8 wk of treatment (mean ± SE)

	CON (n = 10)	MOD (n = 10)	LDY (n = 10)	MDY (n = 10)	HDY (n = 10)	ROS (n = 10)
Body weight (g)	562.73 ± 12.17	424.15 ± 18.30b	412.60 ± 12.89b	444.88 ± 12.02b	445.71 ± 15.54b	470.80 ± 19.9bc
Glu (mmol/L)	3.85 ± 0.33	17.65 ± 2.22b	14.48 ± 0.68b	12.76 ± 0.56bd	12.16 ± 1.00bd	12.70 ± 0.55bd
FINS (pg/mL)	3863.25 ± 316.14	1973.70 ± 237.35a	3025.17 ± 296.30	2275.06 ± 256.45	1815.21 ± 187.26a	2087.53 ± 220.78a
HOMA-IR	16.59 ± 2.65	38.79 ± 9.02b	48.48 ± 4.74b	30.37 ± 3.57	22.68 ± 2.37c	21.66 ± 2.13c
TG (mmol/L)	0.83 ± 0.15	1.99 ± 0.26b	1.88 ± 0.31b	1.19 ± 0.16c	0.87 ± 0.15d	1.05 ± 0.16d
TC (mmol/L)	1.56 ± 0.15	6.50 ± 1.04b	5.80 ± 0.66b	4.51 ± 0.76b	3.31 ± 0.52bd	4.71 ± 0.51b
HDL-c (mmol/L)	1.06 ± 0.14	0.50 ± 0.03b	0.69 ± 0.05b	0.78 ± 0.04d	0.84 ± 0.08d	0.97 ± 0.08d
LDL-c (mmol/L)	0.50 ± 0.05	6.00 ± 1.07b	5.11 ± 0.67b	3.73 ± 0.50b	2.47 ± 0.50bd	3.74 ± 0.49b

Glu: Fasting serum glucose; FINS: Fasting serum insulin; HOMA-IR: Homeostasis model assessment of basal insulin resistance; TG: Triglyceride; TC: Total cholesterol; HDL-c: High-density lipoprotein cholesterol; LDL-c: Low-density lipoprotein cholesterol; CON: Control group; MOD: Type 2 diabetes model group; LDY: Low-dose Yi-Qi-Zeng-Min-Tang (YQZMT) group; MDY: Medium-dose YQZMT group; HDY: High-dose YQZMT group; ROS: Rosiglitazone group.

^aP < 0.05,

^bP < 0.01 vs CON group;

^cP < 0.05,

^dP < 0.01 vs MOD group.