Yi-Qi-Zeng-Min-Tang, a Chinese medicine, ameliorates insulin resistance in type 2 diabetic rats

Table 3 General characteristics of diabetic rats after 4 wk of treatment (mean ± SE)

	CON (n = 10)	MOD (n = 10)	LDY (n = 10)	MDY (n = 10)	HDY (n = 10)	ROS (n = 10)
Body weight (g)	496.20 ± 13.40	418.08 ± 16.06b	434.80 ± 13.15b	433.75 ± 10.99b	443.14 ± 13.15a	439.30 ± 15.27b
Glu (mmol/L)	3.95 ± 0.27	18.40 ± 1.63b	17.57 ± 0.86b	14.35 ± 1.60bc	13.20 ± 0.64bd	13.00 ± 1.29bd
FINS (pg/mL)	3866.43 ± 249.23	9553.83 ± 899.22b	7170.76 ± 739.99b	7228.81 ± 480.47a	7114.41 ± 762.97a	8363.51 ± 564.91b
HOMA-IR	16.02 ± 1.16	191.49 ± 28.32b	133.39 ± 13.41b	99.67 ± 12.97bc	98.99 ± 12.40bc	107.66 ± 13.01bc
TG (mmol/L)	1.38 ± 0.13	2.99 ± 0.56b	2.91 ± 0.47b	2.62 ± 0.44a	2.58 ± 0.77	2.46 ± 0.31a
TC (mmol/L)	2.06 ± 0.11	8.06 ± 0.69b	8.08 ± 0.80b	6.49 ± 1.40b	5.45 ± 0.64bc	7.79 ± 0.78b
HDL-c (mmol/L)	1.02 ± 0.04	0.61 ± 0.08b	0.71 ± 0.07a	0.82 ± 0.07	0.87 ± 0.11c	0.84 ± 0.11
LDL-c (mmol/L)	1.04 ± 0.08	7.46 ± 0.75b	7.37 ± 0.82b	5.67 ± 1.40b	4.58 ± 0.70bd	6.95 ± 0.85b

Glu: Fasting serum glucose; FINS: Fasting serum insulin; HOMA-IR: Homeostasis model assessment of basal insulin resistance; TG: Triglyceride; TC: Total cholesterol; HDL-c: High-density lipoprotein cholesterol; LDL-c: Low-density lipoprotein cholesterol; CON: Control group; MOD: Type 2 diabetes model group; LDY: Low-dose Yi-Qi-Zeng-Min-Tang (YQZMT) group; MDY: Medium-dose YQZMT group; HDY: High-dose YQZMT group; ROS: Rosiglitazone group.

^aP < 0.05,

^bP < 0.01 vs CON group;

^cP < 0.05,

^dP < 0.01 vs MOD group.