Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan

doi:10.3748/wjg.v17.i8.1063

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Feb 28, 2011 (publication date) through Nov 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Feb 28, 2011; 17(8): 1063-1070
Published online Feb 28, 2011. doi: 10.3748/wjg.v17.i8.1063

Table 6 Erythrocytic antioxidative enzyme activities, erythrocytic reduced glutathione/oxidized glutathione ratio and plasma thiobarbituric acid reactive substances concentration of control subjects, patients with hepatitis and cirrhosis alcoholic liver disease (mean ± SE)

	Control	Hepatitis ALD	Cirrhosis ALD
GPX (U/g Hb)	27.9 ± 2.2^a	44.3 ± 8.6^b	28.5 ± 3.8^a
GRD (U/g Hb)	0.55 ± 0.06^a	0.74 ± 0.06^a	0.56 ± 0.07^a
CAT (U/mg Hb)	11.1 ± 0.7^a	10.8 ± 1.2^a	6.4 ± 0.6^b
SOD (U/mg Hb)	9.5 ± 1.6^a	3.7 ± 0.2^b	2.6 ± 0.2^b
GSH/GSSG	38.1 ± 5.4^a	18.3 ± 4.2^b	14.2 ± 1.7^b
TBARS (μmol/L)	3.5 ± 0.2^a	4.2 ± 1.1^a	4.0 ± 0.7^a

Values in the same row with different letters (a, b) significantly different at P < 0.05 (by one-way analysis of variance). ALD: Alcoholic liver disease; GPX: Glutathione peroxidase; GRD: Glutathione reductase; CAT: Catalase; SOD: Superoxide dismutase; GSH: Reduced glutathione; GSSG: Oxidized glutathione; TBARS: Thiobarbituric acid reactive substances.

Citation: Chen YL, Chen LJ, Bair MJ, Yao ML, Peng HC, Yang SS, Yang SC. Antioxidative status of patients with alcoholic liver disease in southeastern Taiwan. World J Gastroenterol 2011; 17(8): 1063-1070
URL: https://www.wjgnet.com/1007-9327/full/v17/i8/1063.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i8.1063