miR-200 family expression is downregulated upon neoplastic progression of Barrett’s esophagus

Table 4 ZEB1 and ZEB2 expression in Barrettt’s epithelium and esophageal adenocarcinoma

	Fold↑	miR-141	miR-200a	miR-200b	miR-200c	miR-429	miR-215
ZEB1	2.9	R = -0.2	R = -0.4	R = -0.5	R = -0.5	R = -0.3	R = -0.3
	P < 0.0001	P = 0.341	P = 0.046	P = 0.009	P = 0.006	P = 0.159	P = 0.152
ZEB2	1.5	R = -0.3	R = -0.3	R = -0.5	R = -0.5	R = -0.4	R = -0.4
	P = 0.029	P = 0.101	P = 0.085	P = 0.008	P = 0.015	P = 0.067	P = 0.044

The fold increase (↑) in median ZEB1 and ZEB2 expression in esophageal adenocarcinoma versus Barrett’s esophagus mucosa from individuals without cancer, and the P value derived using the Mann-Whitney test are given. Spearman correlations (R = Spearman’s rho) between ZEB1/2 expression and each miR-200 member, with associated P values are also shown.