N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer

doi:10.3748/wjg.v17.i6.760

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 17, Issue 6

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (3469)

All Articles published online

The chart showing PDF series, HTML series, Tables (1-4) series.

Item

Count

PDF

387

HTML

2838

Tables (1-4)

244

Sum=3469

Feb 14, 2011 (publication date) through Feb 2, 2025

Times Cited of This Article

Times Cited (20)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Brief Article

World J Gastroenterol. Feb 14, 2011; 17(6): 760-765
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.760

Table 4 Correlation between genotypes and risk for cancer in smokers or ex-smokers

Genetic polymorphism	Cancer, n (%)	Control, n (%)	P	OR (95% CI)
NAT2^a
All	65	87
Mx/Mx	40 (61.5)	39 (44.8)	0.09	1
W/Mx	22 (33.8)	39 (44.8)		1.82 (0.92-3.60)
W/W	3 (4.6)	9 (10.3)		3.08 (0.77-12.22)
Slow	40 (61.5)	39 (44.8)	0.06	1.97 (1.02-3.79)
Fast	25 (38.5)	48 (61.0)

^aHomozygous individuals with genotype W/W, and heterozygote W/Mx, are grouped into fast acetylation phenotype, while homozygous Mx/Mx are grouped in slow acetylators. NAT2: N-acetyltransferase 2; OR: Odds ratio; 95% CI: Confidence interval.

Citation: Silva TDD, Felipe AV, Lima JM, Oshima CTF, Forones NM. N-Acetyltransferase 2 genetic polymorphisms and risk of colorectal cancer. World J Gastroenterol 2011; 17(6): 760-765
URL: https://www.wjgnet.com/1007-9327/full/v17/i6/760.htm
DOI: https://dx.doi.org/10.3748/wjg.v17.i6.760