Original Article
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2011; 17(6): 708-716
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.708
Table 7 Precore and core promoter mutations related to serum hepatitis B virus DNA and alanine aminotransferase in hepatitis B e antigen (-) patients
Serum HBV DNA (log10 IU/mL) (mean ± SD) (n)
P-valueALT (IU/L) [median (min-max)] (n)
P-value
AbsentPresentAbsentPresent
T1762/A176414.64 ± 2.00 (48)5.23 ± 1.79 (60)0.09557.0 (6.0-302) (48)51.5 (6.0-860.0) (60)0.885
A189625.44 ± 1.66 (17)5.91 ± 1.35 (41)0.23146.0 (15.0-860.0) (17)63.5 (14.0-302.0) (41)0.321
A189925.80 ± 1.29 (38)5.72 ± 1.76 (20)0.38252.0 (14.0-860.0) (38)58.5 (17.0-302.0) (20)0.693
T1762/A1764 and A189625.59 ± 1.51 (40)6.17 ± 1.27 (18)0.13865.0 (14.0-860.0) (40)51.0 (17.0-174.0) (18)0.543
T1762/A1764 or A189622.77 ± 4.31 (2)5.88 ± 1.23 (56)< 0.00159.5 (23.0-96.0) (2)52.0 (42.0-860.0) (56)0.847

  • Citation: Utama A, Siburian MD, Purwantomo S, Intan MDB, Kurniasih TS, Gani RA, Achwan WA, Arnelis, Lelosutan SA, Lukito B, Harmono T, Zubir N, Julius, Soemohardjo S, Lesmana LA, Sulaiman A, Tai S. Association of core promoter mutations of hepatitis B virus and viral load is different in HBeAg(+) and HBeAg(-) patients. World J Gastroenterol 2011; 17(6): 708-716
  • URL: https://www.wjgnet.com/1007-9327/full/v17/i6/708.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v17.i6.708