Review
Copyright ©2011 Baishideng Publishing Group Co.
World J Gastroenterol. Feb 14, 2011; 17(6): 697-707
Published online Feb 14, 2011. doi: 10.3748/wjg.v17.i6.697
Table 1 Expression of common markers and translocations in histological subtypes of gastrointestinal lymphomas
TypeCD5CD10CD19CD20CD22CD23CD43CD79aCD3CD7CD4CD8CD30CD15CD45ROAdditional features
Diffuse large B-cell lymphoma-(+)-(+)+++--+-----(+)--(+)Bcl-6+(-), Bcl-2+(-), t (14;18), t (3;14), t (8;14)
MALT lymphoma--+++--(+)+-------(+)t (11;18), t (14;18), t (1;14), t (3;14)
Follicular lymphoma-+(-)+++-(+)-+-----(+)--Bcl-2+, Bcl-6+, t (14;18)
Burkitt lymphoma-++++-(+)++-------C-myc, t (8;14)
Mantle cell lymphoma+-+++-++-------Cyclin D1+, t (11;14)
Peripheral T-cell lymphoma-unspecified+(-)-(+)----+(-)-+(-)-(+)+(-)-(+)-(+)-(+)-(+)-
Extranodal NK/T cell lymphoma-(+)-----+--(+)+(-)-(+)--(+)-(+)-EBV+, gains of 2q, 15q, 17q, 22q, losses of 6q, 8p, 11q, 12q, 13q
EATL------+/--++-(+)+(-)+(-)-+(-)TIA1+, gains of 1q, 5q, 7q, 9q, losses of 8p, 9p, 13q
Hodgkin disease+(-)---(+)----(+)+(-)-(+)--+(-)+(-)-(+)Variable
+: ≥ 90% positive; +(-): > 50% positive; -(+): < 50% positive; -: < 10% positive cases. MALT: Mucosa-associated lymphoid tissue; EATL: Enteropathy-associated T-cell lymphoma; EBV: Epstein-Barr virus.